Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29867906 | 1.00 | MEN1 (0.38) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL30915985 | 0.78 | MAOA (0.48) | MEN1KMT2AALDH1A1MAPTMAOB | |
| SCHEMBL25223676 | 0.78 | ASIC3 (0.44) | RAB9A | |
| SCHEMBL27225510 | 0.75 | NAMPT (0.40) | ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL29867772 | 0.75 | NAMPT (0.40) | ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL14101064 | 0.72 | HSD17B3 (0.42) | MAPTRAB9A | |
| SCHEMBL1528523 | 0.72 | CYP2B6 (0.36) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL14398443 | 0.71 | MAOB (0.53) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL16634768 | 0.71 | ESR2 (0.44) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL12608359 | 0.69 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
| EP-4444313-A1 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| US-20240174615-A1 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2024-05-30 | — | — | US | disclosed |
| CN-117412954-A | Synthesis of rapamycin analog compounds | 锐新医药公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | MLLT1, MEN1, BMI1 | MEN1 2/4885KMT2A 8/4885ALDH1A1 3650/4885 |
| US-20240174615-A1 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | MLST8, MTOR, RICTOR | MEN1 1372/4885KMT2A 3819/4885ALDH1A1 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.