⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075136 | 0.78 | — | — | |
| SCHEMBL25222941 | 0.78 | MAP3K14 (0.32) | — | |
| SCHEMBL24090508 | 0.74 | — | — | |
| SCHEMBL25203490 | 0.70 | P2RX7 (0.42) | — | |
| SCHEMBL25221343 | 0.70 | — | — | |
| SCHEMBL25207090 | 0.67 | L3MBTL1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL29754417 | 0.65 | DRD2 (0.33) | — | |
| SCHEMBL5054785 | 0.62 | CXCR4 (0.38) | — | |
| SCHEMBL5051454 | 0.62 | CXCR4 (0.38) | — | |
| SCHEMBL31482094 | 0.62 | CXCR4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426699-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | Boehringer Ingelheim Vetmedica GmbH (DE) | 2024-09-11 | — | — | EP | disclosed |
| US-20240254133-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-01 | — | — | US | disclosed |
| CN-118339164-A | Insect repellent pyrrolopyridazine compounds | 勃林格殷格翰动物保健有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-11999742-B2 | Substituted pyrrolo[1,2-b]pyridazines as anthelmintics | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-06-04 | — | — | US | disclosed |
| WO-2023073641-A9 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |
| US-20230159543-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230159543-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230159543-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| WO-2023073641-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |