Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.50 |
| ▸ | ME1 | P48163 | 1/20 | 0.50 |
| ▸ | ME3 | Q16798 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30457707 | 0.99 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1POLBCACNA1BPKM | |
| SCHEMBL14115762 | 0.91 | POLB (0.61) | SMN1; SMN2ALDH1A1POLBCACNA1BPKM | |
| SCHEMBL27713178 | 0.85 | ALDH1A1 (0.67) | ALDH1A1POLBME2ME1ME3 | |
| SCHEMBL2539421 | 0.81 | HRH3 (0.56) | ALDH1A1 | |
| SCHEMBL2539413 | 0.81 | HRH3 (0.56) | ALDH1A1 | |
| SCHEMBL31381166 | 0.79 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1POLBPKMME2 | |
| SCHEMBL14115766 | 0.79 | POLB (0.58) | SMN1; SMN2ALDH1A1POLBPKMME2 | |
| SCHEMBL25225367 | 0.78 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1POLBPKMME2 | |
| SCHEMBL13701287 | 0.78 | L3MBTL1 (0.75) | SMN1; SMN2ALDH1A1POLBPKMME2 | |
| SCHEMBL5386665 | 0.77 | NPC1 (0.61) | SMN1; SMN2ALDH1A1POLBCACNA1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023105387-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2023-06-15 | — | — | WO | disclosed |