Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MLNR | O43193 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MC4R | P32245 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23573298 | 0.92 | PKM (0.63) | ALDH1A1SMN1; SMN2PKMMLNRCYP3A4 | |
| SCHEMBL4363650 | 0.83 | EPHX2 (0.56) | ALDH1A1KCNH2EPHX2 | |
| SCHEMBL4363653 | 0.83 | EPHX2 (0.56) | ALDH1A1KCNH2EPHX2 | |
| SCHEMBL30457606 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PKMMLNRCYP3A4 | |
| SCHEMBL23573463 | 0.79 | L3MBTL1 (0.66) | ALDH1A1SIGMAR1POLBTACR3ME3 | |
| SCHEMBL22233497 | 0.78 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2PKMSIGMAR1MAPT | |
| SCHEMBL25225211 | 0.78 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2PKMMLNRCYP3A4 | |
| Hydrochloric Acid SCHEMBL30457707 | 0.77 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2PKMMLNRCYP3A4 | |
| SCHEMBL13701287 | 0.76 | L3MBTL1 (0.75) | ALDH1A1SMN1; SMN2PKMPOLBMAPT | |
| SCHEMBL25272696 | 0.76 | MC4R (0.70) | ALDH1A1SMN1; SMN2PKMMLNRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023105387-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2023-06-15 | — | — | WO | disclosed |