Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30456403 | 0.87 | ACACB (0.41) | — | |
| SCHEMBL30406358 | 0.84 | MAPT (0.35) | MEN1KMT2AHSD17B10CYP2D6CYP3A4 | |
| SCHEMBL25228757 | 0.84 | MEN1 (0.38) | MEN1KMT2AHSD17B10USP2CYP2C9 | |
| SCHEMBL25230302 | 0.82 | ALDH1A1 (0.37) | MEN1KMT2AHSD17B10USP2CYP2D6 | |
| SCHEMBL25627851 | 0.77 | AKT1 (0.39) | MEN1KMT2AHSD17B10USP2CYP2C9 | |
| SCHEMBL25224450 | 0.73 | MEN1 (0.44) | MEN1KMT2AJAK3CYP3A4HPGD | |
| SCHEMBL25276242 | 0.72 | KRAS (0.41) | MEN1KMT2AHSD17B10USP2CYP2C9 | |
| SCHEMBL25423715 | 0.72 | MEN1 (0.38) | MEN1KMT2AHSD17B10USP2CYP2C9 | |
| SCHEMBL30455880 | 0.71 | MAP4K4 (0.47) | HSD17B10CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL30406292 | 0.69 | OPRD1 (0.37) | MEN1HSD17B10CYP2D6CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |