Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 11/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860230 | 0.85 | MGAM (0.46) | GPR88MAPTTSHRTDP1MGAM | |
| SCHEMBL28949355 | 0.84 | MAPT (0.37) | GPR88MAPTTSHRTDP1MGAM | |
| SCHEMBL28314711 | 0.82 | MAPT (0.36) | GPR88MAPTTSHRTDP1MGAM | |
| SCHEMBL28316466 | 0.82 | MAPT (0.36) | GPR88MAPTTSHRTDP1MGAM | |
| SCHEMBL2240017 | 0.82 | TSHR (0.48) | TSHRTDP1MGAMGAASI | |
| SCHEMBL8199981 | 0.80 | MAPT (0.44) | MAPTTSHRMGAMGAASI | |
| SCHEMBL1081187 | 0.80 | MGAM (0.41) | GPR88MAPTTSHRTDP1MGAM | |
| SCHEMBL28949367 | 0.80 | GAA (0.58) | GPR88MAPTTSHRTDP1MGAM | |
| SCHEMBL10168300 | 0.80 | TSHR (0.53) | TSHRTDP1MGAMGAASI | |
| SCHEMBL10168246 | 0.79 | TSHR (0.51) | TSHRCYP3A4ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307854-B | Mixtures of itaconic acid or itaconic acid derivatives with primary amines for the preparation of 1, 3-and 1, 4-alkylmethylpyrrolidones | BASF SE | 2014-11-12 | — | — | CN | disclosed |
| US-8796472-B2 | Mixtures of itaconic acid or itaconic acid derivatives and primary amines for producing 1,3- and 1,4-alkyl methyl pyrrolidones | BASF SE (DE) | 2014-08-05 | — | — | US | disclosed |
| CN-102307854-A | Mixtures of itaconic acid or itaconic acid derivatives with primary amines for the preparation of 1, 3-and 1, 4-alkylmethylpyrrolidones | BASF SE | 2012-01-04 | — | — | CN | disclosed |
| US-20110251119-A1 | MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES | BASF SE (DE) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251119-A1 | MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES | HADHA, HADH, ASS1 | GPR88 1339/4885MAPT 1703/4885TSHR 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.