SCHEMBL25228520

SCHEMBL25228520

CC(C)(C)OC(=O)CCN(CCOCc1ccccc1)C(=O)OCOP(=O)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.43
▸ CTSB P07858 1/20 0.38
▸ PPARA Q07869 1/20 0.35
▸ CCR6 P51684 1/20 0.33
▸ PAX8 Q06710 1/20 0.33
▸ HDAC3 O15379 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ NCOR2 Q9Y618 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25275134 0.91 L3MBTL1 (0.44) L3MBTL1CTSBPPARAHDAC3HDAC1
SCHEMBL25276707 0.88 CCR6 (0.37) L3MBTL1CCR6PAX8HDAC3HDAC1
SCHEMBL25250198 0.88 CCR6 (0.39) L3MBTL1CCR6PAX8ALDH1A1LMNA
SCHEMBL25246646 0.87 L3MBTL1 (0.35) L3MBTL1CCR6PAX8HDAC3HDAC1
SCHEMBL25223781 0.87 CCR6 (0.36) L3MBTL1CCR6PAX8HDAC3HDAC1
SCHEMBL25221576 0.83 L3MBTL1 (0.48) L3MBTL1CTSBPPARACCR6PAX8
SCHEMBL30473565 0.83 L3MBTL1 (0.43) L3MBTL1CTSBPPARAALDH1A1LMNA
SCHEMBL25225313 0.82 CCR6 (0.40) L3MBTL1CCR6PAX8HDAC3HDAC1
SCHEMBL25787817 0.81 CYP3A4 (0.33) —
SCHEMBL25271108 0.81 L3MBTL1 (0.43) L3MBTL1CTSBPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCE INC (US) 2026-02-05 — — US disclosed
US-12404262-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-09-02 — — US disclosed
EP-4440701-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 — — EP disclosed
US-20230212148-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-07-06 — — US disclosed
WO-2023102523-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404262-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 L3MBTL1 1303/4885CTSB 302/4885PPARA 2074/4885
US-20230212148-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION CPSF6, NFATC1, CPSF1 L3MBTL1 611/4885CTSB 708/4885PPARA 2904/4885
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION CCR10, CCR1, CCR3 L3MBTL1 944/4885CTSB 1631/4885PPARA 3141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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