SCHEMBL25250198

SCHEMBL25250198

CC(C)(C)OC(=O)CCN(CCCC(=O)OCc1ccccc1)C(=O)OCOP(=O)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CCR6 P51684 1/20 0.39
▸ PAX8 Q06710 1/20 0.39
▸ ALOX5 P09917 1/20 0.36
▸ L3MBTL1 Q9Y468 3/20 0.36
▸ LMNA P02545 1/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ POLB P06746 1/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ CCKBR P32239 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25217965 0.93 CCR6 (0.37) CCR6PAX8ALOX5L3MBTL1LMNA
SCHEMBL25225313 0.91 CCR6 (0.40) CCR6PAX8ALOX5L3MBTL1KMT2A
SCHEMBL25246646 0.90 L3MBTL1 (0.35) CCR6PAX8L3MBTL1LMNAKMT2A
SCHEMBL25276707 0.89 CCR6 (0.37) CCR6PAX8L3MBTL1POLBALDH1A1
SCHEMBL25223781 0.88 CCR6 (0.36) CCR6PAX8L3MBTL1POLB
SCHEMBL25228520 0.88 L3MBTL1 (0.43) CCR6PAX8L3MBTL1LMNAALDH1A1
SCHEMBL25255619 0.85 ALOX5 (0.37) ALOX5L3MBTL1LMNAKMT2APOLB
SCHEMBL25257371 0.84 CA14 (0.31) —
SCHEMBL30392722 0.84 ALDH1A1 (0.44) L3MBTL1LMNAPOLBALDH1A1MAPK1
SCHEMBL25257598 0.83 CCR6 (0.44) CCR6PAX8ALOX5L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566608-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2025-06-11 — — EP disclosed
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2025-06-05 — — US disclosed
EP-4440702-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 — — EP disclosed
EP-4445900-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 — — EP disclosed
US-12187753-B2 Therapeutics compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-01-07 — — US disclosed
EP-4445900-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2024-10-16 — — EP disclosed
EP-4440702-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 — — EP disclosed
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2024-04-25 — — US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 — — US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 — — US disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS CCR6 33/4885PAX8 4710/4885ALOX5 565/4885
US-11787825-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 CCR6 39/4885PAX8 4627/4885ALOX5 674/4885
US-12187753-B2 Therapeutics compounds for HIV virus infection CD4, HAVCR2, MAVS CCR6 33/4885PAX8 4710/4885ALOX5 565/4885
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION HAVCR2, MAVS, CD4 CCR6 39/4885PAX8 4627/4885ALOX5 674/4885
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS CCR6 33/4885PAX8 4710/4885ALOX5 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback