Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.80 |
| ▸ | CASP1 | P29466 | 5/20 | 0.80 |
| ▸ | CASP7 | P55210 | 5/20 | 0.80 |
| ▸ | TSHR | P16473 | 4/20 | 0.80 |
| ▸ | CFTR | P13569 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14235629 | 0.95 | TAAR1 (1.00) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL5016782 | 0.78 | KDM4E (0.73) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL5016780 | 0.77 | KDM4E (0.71) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL21561037 | 0.74 | TAAR1 (0.64) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL14235251 | 0.72 | CFTR (1.00) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL4005299 | 0.70 | ALDH1A1 (0.70) | KDM4EALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL2522896 | 0.70 | CASP1 (0.62) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL24970930 | 0.70 | TAAR1 (0.57) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL31142938 | 0.70 | TAAR1 (0.57) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL14235249 | 0.69 | CFTR (1.00) | TAAR1KDM4EALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039462-B2 | Alzheimer's disease, stroke, traumatic brain injury, and depression, neurodegenerative diseases; antidepressants; a phenyl thiourea or urea derivatives; promote cell proliferation of stem or progenitor cells | NEURONASCENT, INC. (US) | 2011-10-18 | — | — | US | disclosed |