SCHEMBL25232111

SCHEMBL25232111

N#Cc1ccc(C2([SiH3])CCCCO2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.39
OPRD1 P41143 2/20 0.32
OPRM1 P35372 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
PGR P06401 2/20 0.32
ICMT O60725 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP2A6 P11509 1/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
RORC P51449 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
TRPA1 O75762 1/20 0.31
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28186420 0.86 ESR1 (0.32) ALDH1A1
SCHEMBL27514353 0.84 ESR1 (0.31) ALDH1A1
SCHEMBL2143236 0.79
SCHEMBL25281081 0.79 SLC6A3 (0.42) OPRM1MAOAMAOB
SCHEMBL6122804 0.77
SCHEMBL4447709 0.77 ESR2 (0.48)
SCHEMBL5430518 0.77 SLC6A4 (0.41) ALDH1A1
SCHEMBL43008 0.77 KMT2A (0.34) OPRM1MAOAMAOB
SCHEMBL10953395 0.77
SCHEMBL29099764 0.77 SLC6A4 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114981988-A Metal oxide nanoparticle electron transport layers in perovskite semiconductor devices 立方光伏股份有限公司 2022-08-30 CN claimed
US-11685666-B2 Metal oxide nanoparticles with alkylsiloxane ligands bonded thereto CUBICPV INC. (US) 2023-06-27 US disclosed
CN-114981988-A Metal oxide nanoparticle electron transport layers in perovskite semiconductor devices 立方光伏股份有限公司 2022-08-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685666-B2 Metal oxide nanoparticles with alkylsiloxane ligands bonded thereto MACO1, IPO4, ITGB5 CYP19A1 4451/4885OPRD1 1892/4885OPRM1 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.