SCHEMBL4447709

SCHEMBL4447709

Oc1ccc(C2([SiH3])CCCCO2)cc1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.48
ESR1 P03372 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28186420 0.90 ESR1 (0.32) ESR2ESR1
SCHEMBL27514353 0.88 ESR1 (0.31) ESR2ESR1
Phenol SCHEMBL28289456 0.88 AKR1C1 (0.37) ESR2ESR1
SCHEMBL25281081 0.83 SLC6A3 (0.42)
SCHEMBL2143236 0.83
SCHEMBL5430518 0.81 SLC6A4 (0.41)
SCHEMBL29099764 0.81 SLC6A4 (0.41)
SCHEMBL43008 0.81 KMT2A (0.34)
SCHEMBL10953395 0.81
SCHEMBL28850942 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7632617-B2 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member XEROX CORPORATION (US) 2009-12-15 US claimed
US-7470493-B2 Imaging member XEROX CORPORATION (US) 2008-12-30 US claimed
US-20070020540-A1 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member XEROX CORPORATION 2007-01-25 US claimed
US-20070020539-A1 Imaging member XEROX CORPORATION 2007-01-25 US claimed
EP-0433746-B1 Thermoplastic flame retardant silicone polyphenylene ether graft copolymers GEN ELECTRIC (US) 1995-03-22 EP claimed
CN-112095172-B High-strength high-modulus fine-denier polyarylate fiber and preparation method thereof 宁波海格拉新材料科技有限公司 2023-04-18 CN disclosed
CN-114967331-A Photosensitive dry film 旭化成株式会社 2022-08-30 CN disclosed
CN-112095172-A High-strength high-modulus fine-denier polyarylate fiber and preparation method thereof 宁波海格拉新材料科技有限公司 2020-12-18 CN disclosed
CN-106795297-B Polycarbonate resin composition and molded article thereof 株式会社LG化学 2020-03-10 CN disclosed
CN-104659341-B Composite negative material for lithium ion battery and manufacture method of composite negative material 国联汽车动力电池研究院有限责任公司 2017-05-10 CN disclosed
CN-103140555-B The coating product of anti-flammability coating material aqueous polyurethane resin combination and coating said composition ADEKA CORP. (JP) 2016-06-01 CN disclosed
CN-102264859-B Friction material including a plurality of binder particles having friction modifying particles bound thereto BORGWARNER INC 2014-08-20 CN disclosed
CN-103140555-A Aqueous polyurethane resin composition for flame retardant coated materials and coated products obtained by applying said composition ADEKA CORP 2013-06-05 CN disclosed
CN-102264859-A Friction material including a plurality of binder particles having friction modifying particles bound thereto 2011-11-30 CN disclosed
US-7632617-B2 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member XEROX CORPORATION (US) 2009-12-15 US disclosed
US-20070020540-A1 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member XEROX CORPORATION 2007-01-25 US disclosed
CN-1139626-C Epoxy resin composition and semiconductor device encapsulated therewith ������������ʽ���� 2004-02-25 CN disclosed
CN-1179444-A Epoxy resin composition and semiconductor device encapsulated therewith MITSUBISHI ELECTRIC CORP (JP) 1998-04-22 CN disclosed
US-4496631-A PROPER OIL COMPOSITION PREVENTS FLUFFING AND BREAKING OF PRECURSOR FIBERS TORAY INDUSTRIES, INC. (JP) 1985-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070020540-A1 Silane-phenol compound, overcoat formulation, and electrophotographic imaging member ARNT, STUB1, FLOT1 ESR2 605/4885ESR1 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.