Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 10/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656689 | 0.84 | ALDH1A1 (0.36) | PLAUALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL23301651 | 0.84 | ALDH1A1 (0.36) | PLAUALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL23690319 | 0.75 | KIF20B (0.38) | KIF20BCBFBPLAUALDH1A1KDM4E | |
| SCHEMBL859088 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL23690320 | 0.72 | PDE2A (0.38) | KIF20BCBFBDDR1SMN1; SMN2MAPT | |
| SCHEMBL31358891 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL686704 | 0.71 | PDE4A (0.48) | HTT | |
| SCHEMBL21195950 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2MAPTMAPK1 | |
| SCHEMBL23301676 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2MAPTMAPK1 | |
| SCHEMBL29656844 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049033-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-13 | — | — | US | disclosed |
| CN-118891256-A | Pesticidal activity pyridazinone compounds of (A) | 先正达农作物保护股份公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4444712-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-10-16 | — | — | EP | disclosed |
| WO-2024110554-A1 | N-[(1 -[2-[6-(PYRIDAZIN-3-YL]-1,2,4-TRIAZOL-3-YL]ETHYL]-QUINAZOLIN-4-AMINE AND N-[1-[3-(6-(PYRIDAZIN-3-YL)PYRAZIN-2-YL]ETHYL]-8-QUINAZOLIN-4-AMINE DERIVATIVES AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-30 | — | — | WO | disclosed |
| WO-2023104714-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049033-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | CYP4B1, ACHE, NQO2 | KIF20B 1654/4885CBFB 3497/4885PLAU 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.