Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | AKT1 | P31749 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406267 | 1.00 | PDGFRB (0.41) | PDGFRBCYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL25229702 | 0.92 | AKT1 (0.44) | PDGFRBAKT1JAK3 | |
| SCHEMBL25275689 | 0.89 | PDGFRB (0.43) | PDGFRBCYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL31027420 | 0.86 | KIT (0.44) | PDGFRBCYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL30405888 | 0.84 | PDGFRB (0.41) | PDGFRBCYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL25224450 | 0.83 | MEN1 (0.44) | HPGDCYP3A4AKT1JAK3 | |
| SCHEMBL31501707 | 0.83 | CYP2D6 (0.46) | PDGFRBCYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL25268625 | 0.83 | CYP2D6 (0.46) | PDGFRBCYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL25279193 | 0.82 | AKT1 (0.40) | PDGFRBAKT1MAPK1 | |
| SCHEMBL25281197 | 0.80 | HTT (0.53) | PDGFRBALDH1A1HPGDAKT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |