Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318609 | 0.80 | CYP11B2 (0.44) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL1317272 | 0.71 | ADORA1 (0.34) | KDM1A | |
| SCHEMBL1318233 | 0.71 | CYP11B2 (0.45) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL18151486 | 0.67 | KDM1A (0.55) | KDM1A | |
| SCHEMBL1317860 | 0.67 | ADORA1 (0.37) | KDM1A | |
| SCHEMBL2522497 | 0.66 | KDM1A (0.44) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL2451698 | 0.66 | CCNC (0.40) | — | |
| SCHEMBL1320953 | 0.65 | KDM1A (0.52) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL1319135 | 0.65 | PDPK1 (0.53) | KDM1A | |
| SCHEMBL1319137 | 0.65 | PDPK1 (0.53) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010059658-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |