Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533437 | 0.82 | MTOR (0.39) | KDM1ATLR9TLR8TLR7PIK3CD | |
| SCHEMBL1317131 | 0.78 | KDM1A (0.49) | KDM1AMTORCYP11B1CYP11B2 | |
| SCHEMBL2447251 | 0.78 | KDM1A (0.49) | KDM1AMTORCYP11B1CYP11B2 | |
| SCHEMBL2506224 | 0.68 | PIK3CD (0.46) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL2507060 | 0.68 | CYP11B2 (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL2521058 | 0.67 | EGLN2 (0.39) | KDM1ATLR9TLR8TLR7CYP11B1 | |
| SCHEMBL24699037 | 0.67 | MTOR (0.44) | KDM1AMTORCYP11B1CYP11B2 | |
| SCHEMBL30016357 | 0.67 | MTOR (0.44) | KDM1AMTORCYP11B1CYP11B2 | |
| SCHEMBL1317339 | 0.66 | PDPK1 (0.50) | KDM1AMTORPIK3CG | |
| SCHEMBL2523604 | 0.66 | KDM1A (0.39) | KDM1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010059658-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |