SCHEMBL25237753

SCHEMBL25237753

CCOC(=O)c1c(-c2ccc(Cl)c(Cl)c2)n(CC)c(C)cc1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.46
PTGES O14684 1/20 0.44
ALDH1A1 P00352 4/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
TEAD2 Q15562 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
TP53 P04637 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NOTUM Q6P988 1/20 0.40
BAZ2B Q9UIF8 1/20 0.40
BAZ2A Q9UIF9 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 3/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30457170 1.00 ALOX5 (0.46) ALOX5PTGESALDH1A1SLC6A2SLC6A4
SCHEMBL31114454 0.91 ALOX5 (0.46) ALOX5PTGESALDH1A1SLC6A2SLC6A4
SCHEMBL30504580 0.91 MEN1 (0.50) ALOX5ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL24498772 0.91 MEN1 (0.50) ALOX5ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL31114437 0.88 ALOX5 (0.44) ALOX5PTGESALDH1A1SLC6A2SLC6A4
SCHEMBL31114467 0.88 ALOX5 (0.44) ALOX5PTGESALDH1A1SLC6A2SLC6A4
SCHEMBL31114461 0.88 ALOX5 (0.44) ALOX5PTGESALDH1A1SLC6A2SLC6A4
SCHEMBL10463375 0.88 MEN1 (0.52) ALOX5PTGESALDH1A1GABRA2GABRB2
SCHEMBL30665956 0.87 ALOX5 (0.43) ALOX5PTGESALDH1A1SLC6A2SLC6A4
SCHEMBL9330760 0.86 POLB (0.43) ALDH1A1MEN1KMT2ANOTUMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532467-B1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-03-11 EP disclosed
EP-4532468-B1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-03-11 EP disclosed
US-20260013501-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2026-01-15 US disclosed
US-20250324971-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2025-10-23 US disclosed
EP-4532468-A1 HERBICIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2025-04-09 EP disclosed
EP-4532467-A1 HERBICIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2025-04-09 EP disclosed
US-20250098679-A1 HERBICIDAL PYRIDONE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 US disclosed
CN-119421873-A Herbicidal derivatives 先正达农作物保护股份公司 2025-02-11 CN disclosed
EP-4448509-A1 HERBICIDAL PYRIDONE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-10-23 EP disclosed
CN-118355007-A Herbicidal pyridone derivatives 先正达农作物保护股份公司 2024-07-16 CN disclosed
WO-2023232676-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-12-07 WO disclosed
WO-2023232674-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-12-07 WO disclosed
WO-2023232674-A1 HERBICIDAL DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-12-07 WO disclosed
WO-2023110664-A1 HERBICIDAL PYRIDONE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed
WO-2023110664-A1 HERBICIDAL PYRIDONE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250098679-A1 HERBICIDAL PYRIDONE DERIVATIVES PDXK, DDT, PNPO ALOX5 514/4885PTGES 1461/4885ALDH1A1 46/4885
US-20250324971-A1 HERBICIDAL DERIVATIVES DDT, CYP1B1, CYP1A1 ALOX5 1173/4885PTGES 2497/4885ALDH1A1 12/4885
US-20260013501-A1 HERBICIDAL DERIVATIVES CBR3, CBR1, DDT ALOX5 1080/4885PTGES 3803/4885ALDH1A1 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.