SCHEMBL9330760

SCHEMBL9330760

CCn1c(C)cc(=O)c(C(=O)O)c1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
KMO O15229 5/20 0.39
CCR2 P41597 2/20 0.37
MAP3K14 Q99558 1/20 0.37
KDM2B Q8NHM5 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
NOTUM Q6P988 1/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ITGB1 P05556 1/20 0.35
ITGA4 P13612 1/20 0.35
ITGB7 P26010 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9331326 0.90 POLB (0.41) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL31114609 0.88 POLB (0.43) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL10462411 0.87 POLB (0.43) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL9331352 0.87 ENPP2 (0.40) POLBMEN1KMT2AKDM2BKDM4C
SCHEMBL122379 0.87 KMT2A (0.49) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL24498772 0.86 MEN1 (0.50) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL30457170 0.86 ALOX5 (0.46) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL30504580 0.86 MEN1 (0.50) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL25237753 0.86 ALOX5 (0.46) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL31114421 0.86 POLB (0.42) POLBMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0127313-A1 The production of haploid seed, of doubled haploids and of homozygous plant lines therefrom CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1984-12-05 EP claimed
CN-116547273-A Herbicidal derivatives 先正达农作物保护股份公司 2023-08-04 CN disclosed
EP-0364183-B1 Chemical hybridisation of dicots ZENECA LTD (GB) 1994-03-30 EP disclosed
US-4964896-A GAMETOCIDES MONSANTO COMPANY (US) 1990-10-23 US disclosed
US-4936904-A Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants MONSANTO TECHNOLOGY LLC 1990-06-26 US disclosed
EP-0364183-A2 Chemical hybridisation of dicots ZENECA LIMITED (GB) 1990-04-18 EP disclosed
EP-0127313-B1 THE PRODUCTION OF HAPLOID SEED, OF DOUBLED HAPLOIDS AND OF HOMOZYGOUS PLANT LINES THEREFROM CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-07-19 EP disclosed
US-4714492-A HYBRIDIZATION AGENTS ROHM AND HAAS COMPANY (US) 1987-12-22 US disclosed
EP-0127313-A1 The production of haploid seed, of doubled haploids and of homozygous plant lines therefrom CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1984-12-05 EP disclosed
EP-0040082-B1 NOVEL SUBSTITUTED OXONICOTINATES, THEIR USE AS PLANT GROWTH REGULATORS AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM ROHM AND HAAS COMPANY (US) 1984-04-25 EP disclosed