SCHEMBL25237875

SCHEMBL25237875

O=C(/C=C/c1ccc(O)c([N+](=O)[O-])c1)c1ccc(OCC(=O)N2CCOCC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.59
▸ MAPK1 P28482 4/20 0.59
▸ HTT P42858 4/20 0.59
▸ KMT2A Q03164 3/20 0.59
▸ L3MBTL1 Q9Y468 2/20 0.59
▸ RECQL P46063 1/20 0.59
▸ ATM Q13315 1/20 0.59
▸ KEAP1 Q14145 4/20 0.57
▸ NFE2L2 Q16236 4/20 0.57
▸ NPC1 O15118 3/20 0.56
▸ RAB9A P51151 3/20 0.56
▸ MEN1 O00255 2/20 0.52
▸ POLB P06746 2/20 0.52
▸ MAPT P10636 6/20 0.49
▸ SMN1; SMN2 Q16637 5/20 0.49
▸ LMNA P02545 5/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25192660 0.92 MAPT (0.55) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25188843 0.82 MEN1 (0.62) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25212469 0.82 KEAP1 (0.67) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25196875 0.82 MEN1 (0.62) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25189629 0.82 KEAP1 (0.67) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25198566 0.82 KEAP1 (0.67) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL30383525 0.82 KEAP1 (0.67) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25218218 0.81 MAPT (0.62) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25198669 0.81 MAPT (0.62) ALDH1A1MAPK1HTTKMT2AL3MBTL1
SCHEMBL25223384 0.81 KEAP1 (0.69) ALDH1A1RECQLKEAP1NFE2L2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ALDH1A1 3285/4885MAPK1 3352/4885HTT 149/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885MAPK1 3412/4885HTT 239/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ALDH1A1 3081/4885MAPK1 3412/4885HTT 239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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