Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25198566 | 1.00 | KEAP1 (0.67) | KEAP1NFE2L2MAPTNPC1RAB9A | |
| SCHEMBL25195089 | 0.90 | KEAP1 (0.64) | KEAP1NFE2L2MAPTNPC1RAB9A | |
| SCHEMBL31233177 | 0.90 | KEAP1 (0.64) | KEAP1NFE2L2MAPTNPC1RAB9A | |
| SCHEMBL25189629 | 0.88 | KEAP1 (0.67) | KEAP1NFE2L2MAPTALDH1A1HTT | |
| SCHEMBL25212469 | 0.88 | KEAP1 (0.67) | KEAP1NFE2L2MAPTALDH1A1HTT | |
| SCHEMBL30383954 | 0.83 | KEAP1 (0.69) | KEAP1NFE2L2MAPTALDH1A1KDM4E | |
| SCHEMBL25198003 | 0.83 | KEAP1 (0.69) | KEAP1NFE2L2MAPTALDH1A1KDM4E | |
| SCHEMBL25223384 | 0.83 | KEAP1 (0.69) | KEAP1NFE2L2MAPTALDH1A1KDM4E | |
| SCHEMBL25237875 | 0.82 | ALDH1A1 (0.59) | KEAP1NFE2L2MAPTNPC1RAB9A | |
| SCHEMBL25221774 | 0.80 | MAPT (1.00) | KEAP1NFE2L2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |