Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.49 |
| ▸ | MET | P08581 | 6/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 6/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30465792 | 0.87 | FLT3 (0.46) | FLT3METFGFR2AXLSRC | |
| SCHEMBL30465529 | 0.84 | AXL (0.51) | FLT3METAXL | |
| SCHEMBL25285080 | 0.84 | FGFR2 (0.42) | FLT3METFGFR2AXLRET | |
| SCHEMBL30465735 | 0.84 | FGFR2 (0.44) | FLT3FGFR2AXLSRCTGFBR1 | |
| SCHEMBL30465700 | 0.83 | FLT3 (0.44) | FLT3METFGFR2AXLSRC | |
| SCHEMBL30465769 | 0.81 | FGFR2 (0.43) | FLT3METFGFR2AXLRET | |
| SCHEMBL30465768 | 0.81 | FLT3 (0.44) | FLT3METFGFR2AXLSRC | |
| SCHEMBL30465415 | 0.79 | AXL (0.67) | FLT3METFGFR2AXLSRC | |
| SCHEMBL25279725 | 0.79 | MET (0.41) | FLT3METFGFR2AXLSRC | |
| SCHEMBL30465511 | 0.79 | MET (0.43) | FLT3METFGFR2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |