Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161701 | 0.87 | ALDH1A1 (0.50) | TDP1ATMMEN1KMT2ATTR | |
| SCHEMBL27357985 | 0.84 | ATM (0.51) | TDP1ATMMEN1KMT2ARAPGEF3 | |
| SCHEMBL7549531 | 0.81 | TDP1 (0.49) | TDP1ATMMEN1KMT2ARAPGEF3 | |
| SCHEMBL28474988 | 0.81 | TSHR (0.53) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6036166 | 0.80 | ELANE (0.47) | TDP1ATMMEN1KMT2ARAPGEF3 | |
| SCHEMBL28655379 | 0.80 | TDP1 (0.47) | TDP1ATMMEN1KMT2ARAPGEF3 | |
| SCHEMBL4687248 | 0.80 | HSPB1 (0.45) | TDP1ATMMEN1KMT2AKIF11 | |
| SCHEMBL17786752 | 0.79 | ATM (0.62) | TDP1ATMMEN1KMT2ARAPGEF3 | |
| SCHEMBL2937774 | 0.79 | ATM (0.46) | TDP1ATMMEN1KMT2ARAPGEF3 | |
| SCHEMBL28911140 | 0.79 | KMT2A (0.53) | TDP1ATMMEN1KMT2ARAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406360-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-113444016-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-107734969-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-06-01 | — | — | CN | disclosed |