Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | EGFR | P00533 | 6/20 | 0.63 |
| ▸ | ERBB3 | P21860 | 5/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.59 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1321858 | 0.79 | MAPT (0.64) | KMT2AMEN1NPC1RAB9AEGFR | |
| SCHEMBL25284382 | 0.79 | HPGD (0.51) | KMT2AMEN1NPC1EGFRERBB3 | |
| SCHEMBL25293421 | 0.79 | GAA (0.53) | KMT2AMEN1NPC1RAB9AEGFR | |
| SCHEMBL25242554 | 0.78 | POLB (0.47) | KMT2AMEN1EGFRERBB3TP53 | |
| SCHEMBL20355108 | 0.78 | MAPT (0.66) | KMT2AMEN1NPC1RAB9AEGFR | |
| SCHEMBL20355235 | 0.78 | RAB9A (0.72) | KMT2AMEN1NPC1RAB9AEGFR | |
| SCHEMBL25288885 | 0.77 | POLB (0.48) | KMT2AMEN1NPC1RAB9AEGFR | |
| SCHEMBL855961 | 0.76 | EGFR (0.77) | KMT2AMEN1NPC1RAB9AEGFR | |
| SCHEMBL25244650 | 0.75 | TYK2 (0.59) | MAPTPOLB | |
| SCHEMBL25288507 | 0.75 | POLB (0.46) | KMT2AMEN1NPC1RAB9AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |