Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242417 | 0.77 | POLB (0.40) | TYK2POLBGAALCKIGF1R | |
| SCHEMBL25289334 | 0.75 | MAPT (0.31) | TYK2 | |
| SCHEMBL25290618 | 0.73 | PIK3CA (0.40) | TYK2 | |
| SCHEMBL25293423 | 0.72 | POLB (0.51) | TYK2POLBGAALCKIGF1R | |
| SCHEMBL25286435 | 0.68 | TYK2 (0.51) | TYK2 | |
| SCHEMBL25246314 | 0.67 | TYK2 (0.39) | TYK2 | |
| SCHEMBL25243602 | 0.67 | TYK2 (0.49) | TYK2 | |
| SCHEMBL25289232 | 0.67 | TYK2 (0.61) | TYK2 | |
| SCHEMBL25243763 | 0.66 | POLB (0.46) | TYK2POLBGAALCKIGF1R | |
| SCHEMBL25245407 | 0.62 | GRM5 (0.41) | POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |