Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286435 | 0.84 | TYK2 (0.51) | TYK2 | |
| SCHEMBL25282951 | 0.81 | TYK2 (0.43) | TYK2 | |
| SCHEMBL25243733 | 0.75 | TYK2 (0.38) | TYK2 | |
| SCHEMBL25285840 | 0.74 | GRM5 (0.48) | TYK2 | |
| SCHEMBL25250005 | 0.71 | TYK2 (0.54) | TYK2 | |
| SCHEMBL25286901 | 0.70 | TTK (0.38) | TYK2PDE2A | |
| SCHEMBL25245407 | 0.70 | GRM5 (0.41) | — | |
| SCHEMBL25292442 | 0.69 | TTK (0.41) | TYK2 | |
| SCHEMBL25284382 | 0.66 | HPGD (0.51) | — | |
| SCHEMBL25293421 | 0.65 | GAA (0.53) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |