Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 8/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239477 | 0.83 | TTK (0.48) | TTKLRRK2CCNA2CDK2 | |
| SCHEMBL25286994 | 0.79 | TYK2 (0.31) | — | |
| SCHEMBL25292442 | 0.78 | TTK (0.41) | TTKLRRK2CCNA2CDK2 | |
| SCHEMBL25285749 | 0.73 | TYK2 (0.36) | TTKLRRK2SLC34A1 | |
| SCHEMBL25286881 | 0.71 | TTK (0.57) | TTKLRRK2CCNA2CDK2 | |
| SCHEMBL25242862 | 0.69 | TTK (0.41) | TTKLRRK2SLC34A1 | |
| SCHEMBL25241283 | 0.67 | PIK3C3 (0.34) | CD274 | |
| SCHEMBL25283616 | 0.66 | PIK3C3 (0.34) | — | |
| SCHEMBL25245407 | 0.63 | GRM5 (0.41) | EGFRMEN1KMT2A | |
| SCHEMBL13321937 | 0.59 | MAPK10 (0.61) | CDK2EGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |