Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877449 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1MMP2MMP3MMP1 | |
| SCHEMBL2526531 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2EPHX1MMP2MMP3MMP1 | |
| SCHEMBL13688891 | 0.96 | SMN1; SMN2 (0.42) | SMN1; SMN2EPHX1MMP2MMP3MMP1 | |
| SCHEMBL30980846 | 0.85 | EPHX1 (0.41) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL30980900 | 0.85 | EPHX1 (0.41) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL3136912 | 0.84 | PTGS1 (0.41) | SMN1; SMN2MMP2MMP3MMP1MMP7 | |
| SCHEMBL1337928 | 0.84 | TDP1 (0.42) | SMN1; SMN2MMP2MMP3MMP1MMP7 | |
| SCHEMBL31196416 | 0.81 | ALOX15 (0.38) | SMN1; SMN2EPHX1MMP2CA2MAPK1 | |
| SCHEMBL28835158 | 0.80 | PDF (0.40) | EPHX1MMP2MMP3MMP1MMP7 | |
| SCHEMBL28835157 | 0.80 | PDF (0.40) | EPHX1MMP2MMP3MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8728771-B2 | L-succinylaminoacylase and process for producing L-amino acid using it | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2014-05-20 | — | — | US | disclosed |
| US-8470574-B2 | L-succinylaminoacylase and process for producing L-amino acid using it | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20110250653-A1 | L-SUCCINYLAMINOACYLASE AND PROCESS FOR PRODUCING L-AMINO ACID USING IT | SEKISUI MEDICAL CO., LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
| US-20110244530-A1 | L-SUCCINYLAMINOACYLASE AND PROCESS FOR PRODUCING L-AMINO ACID USING IT | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-10-06 | — | — | US | disclosed |