Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337928 | 0.96 | TDP1 (0.42) | PTGS1KCNH2TDP1MMP1MMP2 | |
| SCHEMBL2524548 | 0.84 | SMN1; SMN2 (0.46) | MMP1MMP2MMP3MMP7SMN1; SMN2 | |
| SCHEMBL13688891 | 0.84 | SMN1; SMN2 (0.42) | MMP1MMP2MMP3MMP7SMN1; SMN2 | |
| SCHEMBL10877449 | 0.84 | SMN1; SMN2 (0.46) | MMP1MMP2MMP3MMP7SMN1; SMN2 | |
| SCHEMBL2526531 | 0.84 | SMN1; SMN2 (0.46) | MMP1MMP2MMP3MMP7SMN1; SMN2 | |
| SCHEMBL10230795 | 0.79 | CA2 (0.35) | MEN1GAAKMT2ACA2 | |
| SCHEMBL10230783 | 0.79 | CA2 (0.35) | MEN1GAAKMT2ACA2 | |
| SCHEMBL2429929 | 0.78 | MAPT (0.40) | MMP1MMP2MMP3MMP7ALDH1A1 | |
| SCHEMBL3749598 | 0.78 | GGT1 (0.42) | PTGS1ALDH1A1CA2 | |
| SCHEMBL12937421 | 0.74 | CA2 (0.34) | PTGS1TDP1MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7641914-B2 | for forming conjugates (liposomes, complexes, nanoparticles) with biologically active substances and releasing them into cellular tissues or acidic compartments, or for use as nonionic surfactant for stabilizing particles encapsulating biodrugs | GENCELL, S.A. (FR) | 2010-01-05 | — | — | US | disclosed |
| US-20050222434-A1 | Acid-sensitive compounds, their preparation and uses | GENCELL S.A. | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222434-A1 | Acid-sensitive compounds, their preparation and uses | LIPA, PHOSPHO1, ACP1 | PTGS1 2809/4885KCNH2 4597/4885TDP1 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.