SCHEMBL25245752

SCHEMBL25245752

CC(C)(C)OC(=O)COCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.53
USP30 Q70CQ3 2/20 0.37
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
DGAT1 O75907 1/20 0.36
AAK1 Q2M2I8 2/20 0.35
SCN9A Q15858 1/20 0.33
BACE1 P56817 1/20 0.33
BACE2 Q9Y5Z0 1/20 0.33
JAK3 P52333 1/20 0.32
HIF1A Q16665 1/20 0.31
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21421680 0.98 FFAR1 (0.51) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL21405360 0.98 FFAR1 (0.51) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL18551339 0.93 FFAR1 (0.50) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL24540152 0.89 FFAR1 (0.51) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL21421693 0.89 FFAR1 (0.48) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL1725558 0.86 FFAR1 (0.57) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL25291902 0.84 FFAR1 (0.50) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL844227 0.83 FFAR1 (0.60) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL18530455 0.83 FFAR1 (0.54) FFAR1USP30PRMT5WDR77DGAT1
SCHEMBL25248137 0.82 FFAR1 (0.53) FFAR1USP30PRMT5WDR77DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-04-10 US disclosed
EP-4452978-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2024-10-30 EP disclosed
WO-2023115150-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 WO disclosed
WO-2023115150-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 FFAR1 1395/4885USP30 1167/4885PRMT5 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.