Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455030 | 0.88 | PDE4A (0.57) | KMT2AMEN1RAB9ATSHRGAA | |
| SCHEMBL10455031 | 0.88 | PDE4A (0.57) | KMT2AMEN1RAB9ATSHRGAA | |
| SCHEMBL10386517 | 0.84 | CYP1A2 (0.58) | RAB9ATSHRGAAMAPTLMNA | |
| SCHEMBL10386519 | 0.84 | CYP1A2 (0.58) | RAB9ATSHRGAAMAPTLMNA | |
| SCHEMBL22208934 | 0.84 | HTT (0.57) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| SCHEMBL9367554 | 0.83 | CA12 (0.62) | TSHRKDM4EGAAMAPTLMNA | |
| SCHEMBL10610492 | 0.82 | TAS1R3 (0.50) | HPGDCA12CA1CA2CA4 | |
| SCHEMBL10610489 | 0.82 | TAS1R3 (0.50) | HPGDCA12CA1CA2CA4 | |
| SCHEMBL2954277 | 0.82 | TSHR (0.62) | RAB9ATSHRKDM4EGAAMAPT | |
| SCHEMBL10609792 | 0.81 | ALDH1A1 (0.58) | HTTRAB9ALMNACYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039513-B2 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2011-10-18 | — | — | US | disclosed |
| US-7759527-B2 | Microwave induced one pot process for the preparation of arylethenes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20080045752-A1 | Microwave Induced One Pot Process For The Preparation Of Arylethenes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045752-A1 | Microwave Induced One Pot Process For The Preparation Of Arylethenes | TET2, HCN4, KDM4E | HTT 2179/4885KMT2A 36/4885SLC22A6 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.