Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 15/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286435 | 0.87 | TYK2 (0.51) | TYK2 | |
| SCHEMBL25250005 | 0.86 | TYK2 (0.54) | TYK2 | |
| SCHEMBL25290618 | 0.85 | PIK3CA (0.40) | TYK2PIK3CAJAK3 | |
| SCHEMBL25245420 | 0.84 | TYK2 (0.51) | TYK2 | |
| SCHEMBL25246314 | 0.81 | TYK2 (0.39) | TYK2 | |
| SCHEMBL25238998 | 0.74 | TYK2 (0.39) | TYK2PIK3CA | |
| SCHEMBL25247661 | 0.74 | TYK2 (0.39) | TYK2PIK3CA | |
| SCHEMBL25292519 | 0.74 | TYK2 (0.39) | TYK2PIK3CA | |
| SCHEMBL25249498 | 0.73 | TYK2 (0.51) | TYK2 | |
| SCHEMBL25243602 | 0.73 | TYK2 (0.49) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |