Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.38 |
| ▸ | TYK2 | P29597 | 8/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25240286 | 0.82 | TYK2 (0.47) | TYK2 | |
| SCHEMBL25284382 | 0.78 | HPGD (0.51) | EGFRGAA | |
| SCHEMBL25238174 | 0.77 | NPC1 (0.44) | TTKEGFRPOLBGAA | |
| SCHEMBL25283961 | 0.77 | EGFR (0.48) | TTKTYK2JAK1EGFRPOLB | |
| SCHEMBL25248456 | 0.77 | TYK2 (0.51) | TYK2 | |
| SCHEMBL25292409 | 0.76 | TYK2 (0.52) | TYK2 | |
| SCHEMBL25293421 | 0.76 | GAA (0.53) | TYK2JAK2JAK1JAK3EGFR | |
| SCHEMBL25246078 | 0.75 | TTK (0.37) | TTKEGFRPOLBGAA | |
| SCHEMBL25289693 | 0.74 | S1PR1 (0.39) | TTK | |
| SCHEMBL25242828 | 0.74 | LRRK2 (0.47) | TTKEGFRPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |