Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MLYCD | O95822 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15881788 | 0.87 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 | |
| SCHEMBL13884195 | 0.87 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 | |
| SCHEMBL185921 | 0.86 | MLYCD (0.63) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 | |
| SCHEMBL249436 | 0.84 | L3MBTL1 (0.61) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 | |
| SCHEMBL17231401 | 0.84 | MLYCD (0.60) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL4501943 | 0.84 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 | |
| SCHEMBL23135794 | 0.83 | SMN1; SMN2 (0.63) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 | |
| SCHEMBL24713109 | 0.83 | MLYCD (0.67) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL30661718 | 0.81 | MLYCD (0.65) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 | |
| SCHEMBL2420380 | 0.81 | L3MBTL1 (0.68) | L3MBTL1NPC1RAB9AMLYCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-B1 | NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY | RESPIRATORIUS AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| EP-2401275-B1 | NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY | RESPIRATORIUS AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| US-8415333-B2 | Bronchodilating diazaheteroaryls | RESPIRATORIOUS AB (SE) | 2013-04-09 | — | — | US | disclosed |
| US-8415333-B2 | Bronchodilating diazaheteroaryls | RESPIRATORIOUS AB (SE) | 2013-04-09 | — | — | US | disclosed |
| US-8415333-B2 | Bronchodilating diazaheteroaryls | RESPIRATORIOUS AB (SE) | 2013-04-09 | — | — | US | disclosed |
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2012-02-16 | — | — | US | disclosed |
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2012-02-16 | — | — | US | disclosed |
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2012-02-16 | — | — | US | disclosed |
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |
| EP-0200134-B1 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4910315-A | Containing a phenyl substitution | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-03-20 | — | — | US | disclosed |
| US-4736038-A | IMMUNOLOGY | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0200134-A2 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040942-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | CHRM3, ADRB1, ADRB3 | L3MBTL1 3730/4885NPC1 1797/4885RAB9A 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.