SCHEMBL252499

SCHEMBL252499

NC(=O)n1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31648205 0.78 GAA (0.33)
SCHEMBL20604684 0.77 TYMP (0.32)
Urea SCHEMBL9301106 0.70 LMNA (0.46) JAK2THRB
SCHEMBL17849940 0.68 JAK2 (0.32) JAK2THRB
SCHEMBL9420757 0.67 NSD2 (0.31)
SCHEMBL28705743 0.67 TYMP (0.39)
SCHEMBL2169311 0.65 DAO (0.41)
SCHEMBL28606 0.65 TYMP (0.31)
SCHEMBL3480363 0.65 ALDH1A1 (0.38)
SCHEMBL31621004 0.64 TYMP (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002536-A1 MANUFACTURE OF FIBER REINFORCED COMPOSITE MATERIALS WITH ISOCYANATE RESIN TRIMER TECHNOLOGIES, LLC (US) 2023-01-05 US claimed
WO-2021081154-A1 MANUFACTURE OF FIBER REINFORCED COMPOSITE MATERIALS WITH ISOCYANATE RESIN SODANO HENRY A (US) 2021-04-29 WO claimed
EP-1326573-B1 ADHESIVE FOR USE IN THE ORAL ENVIRONMENT HAVING COLOR-CHANGING CAPABILITIES 3M INNOVATIVE PROPERTIES CO (US) 2016-08-24 EP claimed
US-6528555-B1 Photobleachable dye, orthodontics 3M INNOVATIVE PROPERTIES COMPANY 2003-03-04 US claimed
EP-0209365-B1 COMPOSITIONS CONTAINING POLY(ETHYLENICALLY UNSATURATED)CARBAMOYL ISOCYANURATES AND THEIR USE FOR DENTAL TREATMENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-18 EP claimed
US-4648843-A Method of dental treatment using poly(ethylenically unsaturated) carbamoyl isocyanurates and dental materials made therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-10 US claimed
EP-0209365-A2 Compositions containing poly(ethylenically unsaturated)carbamoyl isocyanurates and their use for dental treatment MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-21 EP claimed
EP-3265049-B1 COMPOSITE MATERIAL HAVING CERAMIC FIBERS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-05-01 EP disclosed
US-11759404-B2 Porous composite filler compositions KERR CORPORATION (US) 2023-09-19 US disclosed
US-20230000596-A1 DENTAL APPLIANCE WITH A SURFACE HAVING PATTERNED GLASS IONOMER COATING SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-01-05 US disclosed
CN-106963656-B Block composite material for dental cutting having fiber-containing material with multilayer structure having different transparency 株式会社松风 2022-02-22 CN disclosed
US-20210315664-A1 COMPOSITE MATERIALS INCLUDING CERAMIC FIBERS AND NANOCLUSTERS, DENTAL PRODUCTS, KITS, AND METHODS OF MAKING AND USING SAME SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2021-10-14 US disclosed
US-11141247-B2 Block-like composite material for dental cutting and processing having multilayered structure including layers with different transparencies and containing fiber material SHOFU INC. (JP) 2021-10-12 US disclosed
WO-2001030307-A1 DENTAL MATERIALS WITH NANO-SIZED SILICA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-05-03 WO disclosed
EP-0209365-B1 COMPOSITIONS CONTAINING POLY(ETHYLENICALLY UNSATURATED)CARBAMOYL ISOCYANURATES AND THEIR USE FOR DENTAL TREATMENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-18 EP disclosed
EP-0209365-B1 COMPOSITIONS CONTAINING POLY(ETHYLENICALLY UNSATURATED)CARBAMOYL ISOCYANURATES AND THEIR USE FOR DENTAL TREATMENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-18 EP disclosed
US-4648843-A Method of dental treatment using poly(ethylenically unsaturated) carbamoyl isocyanurates and dental materials made therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-10 US disclosed
EP-0209365-A2 Compositions containing poly(ethylenically unsaturated)carbamoyl isocyanurates and their use for dental treatment MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-21 EP disclosed
EP-0209365-A2 Compositions containing poly(ethylenically unsaturated)carbamoyl isocyanurates and their use for dental treatment MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-21 EP disclosed
US-3933694-A Low smoke-output polyurethane and polyisocyanurate foams OWENS-CORNING FIBERGLAS CORPORATION (US) 1976-01-20 US disclosed