Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245324 | 1.00 | HRH3 (0.50) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL25251045 | 0.93 | HRH3 (0.44) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL30245124 | 0.93 | HRH3 (0.44) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL30244917 | 0.93 | HRH3 (0.49) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL25253058 | 0.93 | HRH3 (0.49) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL25252797 | 0.92 | QPCT (0.43) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL30245662 | 0.92 | QPCT (0.43) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL25258029 | 0.90 | HRH3 (0.45) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL30245213 | 0.90 | HRH3 (0.45) | HRH3MAPTHTTQPCTKDM4E | |
| SCHEMBL25257585 | 0.90 | HRH3 (0.40) | HRH3MAPTHTTQPCTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |