Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245124 | 1.00 | HRH3 (0.44) | HRH3CETPKDM4EMAOBKIT | |
| SCHEMBL25250533 | 0.93 | HRH3 (0.50) | HRH3CETPKDM4EQPCTLTA4H | |
| SCHEMBL30245324 | 0.93 | HRH3 (0.50) | HRH3CETPKDM4EQPCTLTA4H | |
| SCHEMBL25295970 | 0.93 | LTA4H (0.43) | HRH3KDM4EMAOBKITFLT3 | |
| SCHEMBL30245340 | 0.91 | HRH3 (0.40) | HRH3CETPKDM4EQPCTLTA4H | |
| SCHEMBL25257585 | 0.91 | HRH3 (0.40) | HRH3CETPKDM4EQPCTLTA4H | |
| SCHEMBL30244966 | 0.90 | HRH3 (0.40) | HRH3KDM4EKITFLT3QPCT | |
| SCHEMBL25250353 | 0.90 | HRH3 (0.40) | HRH3KDM4EKITFLT3QPCT | |
| SCHEMBL25254098 | 0.89 | AGXT (0.46) | HRH3CETPKDM4EQPCTAGXT | |
| SCHEMBL30245329 | 0.89 | AGXT (0.46) | HRH3CETPKDM4EQPCTAGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |