Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 5/20 | 0.46 |
| ▸ | FPGS | Q05932 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298843 | 1.00 | DHFR (0.46) | DHFRFPGS | |
| SCHEMBL24343802 | 0.93 | TDP1 (0.40) | DHFR | |
| SCHEMBL25301066 | 0.89 | DHFR (0.48) | DHFRFPGS | |
| SCHEMBL25301067 | 0.89 | DHFR (0.48) | DHFRFPGS | |
| SCHEMBL25257994 | 0.87 | TYMS (0.40) | DHFR | |
| SCHEMBL25294982 | 0.87 | TYMS (0.40) | DHFR | |
| SCHEMBL30947423 | 0.84 | DHFR (0.54) | DHFRFPGS | |
| SCHEMBL31143686 | 0.84 | DHFR (0.54) | DHFRFPGS | |
| SCHEMBL24344221 | 0.82 | DHFR (0.40) | DHFR | |
| SCHEMBL25171614 | 0.81 | DHFR (0.48) | DHFRFPGS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |