SCHEMBL25251992

SCHEMBL25251992

CC1(C)COB(c2ccc(C(F)=C(F)F)cc2)OC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.36
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4264297 0.82 SNCA (0.44) SNCALPLLIPG
SCHEMBL12370780 0.78 L3MBTL1 (0.38) SNCA
SCHEMBL8083423 0.78 TSHR (0.41) SNCA
SCHEMBL9935185 0.77 SNCA (0.40) SNCALPLLIPG
SCHEMBL1136930 0.77 LPL (0.52) SNCALPLLIPG
SCHEMBL4257326 0.76 SNCA (0.48) SNCALPLLIPG
SCHEMBL12370809 0.74 SNCA (0.41) SNCALPLLIPG
SCHEMBL2273662 0.74 NPC1 (0.56) SNCA
SCHEMBL5524734 0.73 SNCA (0.40) SNCALPLLIPG
SCHEMBL5528199 0.73 SNCA (0.40) SNCALPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2684859-B1 PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS UNIV OSAKA (JP) 2023-06-14 EP disclosed