Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 3/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264297 | 0.89 | SNCA (0.44) | SNCALPLLIPG | |
| SCHEMBL2274567 | 0.83 | LPL (0.42) | SNCALPLLIPG | |
| SCHEMBL4257326 | 0.83 | SNCA (0.48) | SNCALPLLIPG | |
| SCHEMBL12370809 | 0.82 | SNCA (0.41) | SNCALPLLIPG | |
| SCHEMBL28543193 | 0.81 | LPL (0.34) | TAAR1LPLLIPG | |
| SCHEMBL3186952 | 0.80 | SNCA (0.40) | SNCALPLLIPG | |
| SCHEMBL5524734 | 0.80 | SNCA (0.40) | SNCALPLLIPGCYP2A6 | |
| SCHEMBL1136930 | 0.80 | LPL (0.52) | SNCALPLLIPGALDH1A1 | |
| SCHEMBL3711441 | 0.80 | SNCA (0.40) | SNCALPLLIPG | |
| SCHEMBL9935185 | 0.80 | SNCA (0.40) | SNCALPLLIPGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037905-B2 | Pharmaceutical use of boronic acids and esters thereof | NOVO NORDISK A/S (DK) | 2006-05-02 | — | — | US | claimed |
| US-20040053889-A1 | Pharmaceutical use of boronic acids and esters thereof | NOVO NORDISK A/S (DK) | 2004-03-18 | — | — | US | claimed |
| WO-2003105860-A1 | PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 2003-12-24 | — | — | WO | claimed |
| US-9802963-B2 | Fluorine-containing complex compound, and production method for fluorine-containing organic compound employing same | DAIKIN INDUSTRIES, LTD. (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20160214999-A1 | FLUORINE-CONTAINING COMPLEX COMPOUND, AND PRODUCTION METHOD FOR FLUORINE-CONTAINING ORGANIC COMPOUND EMPLOYING SAME | DAIKIN INDUSTRIES, LTD. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-20070105826-A1 | Novel fusidic acid derivatives | LEO PHARMA A/S (DK) | 2007-05-10 | — | — | US | disclosed |
| EP-1658305-A1 | NOVEL FUSIDIC ACID DERIVATIVES | Leo Pharma A/S (DK) | 2006-05-24 | — | — | EP | disclosed |
| US-7037905-B2 | Pharmaceutical use of boronic acids and esters thereof | NOVO NORDISK A/S (DK) | 2006-05-02 | — | — | US | disclosed |
| WO-2005007669-A1 | NOVEL FUSIDIC ACID DERIVATIVES | LEO PHARMA A/S (DK) | 2005-01-27 | — | — | WO | disclosed |
| US-20040053889-A1 | Pharmaceutical use of boronic acids and esters thereof | NOVO NORDISK A/S (DK) | 2004-03-18 | — | — | US | disclosed |
| WO-2003105860-A1 | PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053889-A1 | Pharmaceutical use of boronic acids and esters thereof | LIPE, CEL, LIPA | SNCA 2698/4885TAAR1 3412/4885LPL 5/4885 |
| US-20160214999-A1 | FLUORINE-CONTAINING COMPLEX COMPOUND, AND PRODUCTION METHOD FOR FLUORINE-CONTAINING ORGANIC COMPOUND EMPLOYING SAME | AFF1, AFF2, AFF4 | SNCA 1133/4885TAAR1 198/4885LPL 4234/4885 |
| US-20070105826-A1 | Novel fusidic acid derivatives | FUS, Q6ZSR9, RPL24 | SNCA 4592/4885TAAR1 4846/4885LPL 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.