Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246356 | 0.89 | SMN1; SMN2 (0.41) | KMT2AMEN1RAB9AL3MBTL1MAPT | |
| SCHEMBL11829181 | 0.83 | KMT2A (0.42) | KMT2AMEN1RAB9AL3MBTL1MAPT | |
| SCHEMBL15522753 | 0.79 | NPC1 (0.40) | KMT2AMEN1RAB9AL3MBTL1MAPT | |
| SCHEMBL25294499 | 0.79 | CFD (0.43) | KMT2AMEN1RAB9AMAPTALDH1A1 | |
| SCHEMBL9027345 | 0.79 | RAB9A (0.54) | KMT2AMEN1RAB9AL3MBTL1MAPT | |
| SCHEMBL26961596 | 0.78 | MAPK1 (0.45) | KMT2AMEN1RAB9AL3MBTL1MAPT | |
| SCHEMBL20774839 | 0.76 | MEN1 (0.52) | KMT2AMEN1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL30007195 | 0.76 | SCD (0.39) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL17304125 | 0.76 | SCD (0.39) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL25296877 | 0.75 | RAB9A (0.38) | KMT2AMEN1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291193-A1 | EGFR DEGRADERS AND METHODS OF USE | BeiGene Switzerland GmbH (CH) | 2023-12-20 | — | — | EP | disclosed |
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |