Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.52 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022965 | 0.86 | HTT (1.00) | HTTMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL25297956 | 0.81 | HRH3 (0.61) | HRH3CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11350421 | 0.80 | RAB9A (0.82) | HTTMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10236929 | 0.80 | RAB9A (0.82) | HTTMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27651636 | 0.78 | CYP3A4 (0.70) | HRH3MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL3996341 | 0.77 | ADRB2 (0.51) | HTTHRH3MAPTTP53ADRB2 | |
| SCHEMBL5681498 | 0.77 | PORCN (0.60) | HTTHRH3MAPTNPC1RAB9A | |
| SCHEMBL3030365 | 0.76 | ADRB2 (0.58) | HTTHRH3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25252707 | 0.76 | CYP2D6 (0.56) | HRH3LMNACYP3A4CYP26A1CYP1A2 | |
| SCHEMBL3729907 | 0.76 | NPC1 (0.75) | HTTMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2023083178-A | PHENYLAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | 学校法人常翔学園 | 2023-06-15 | — | — | JP | disclosed |