Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230953 | 0.76 | BRPF1 (0.46) | BRPF1BRD4ANPEPDPP4NPC1 | |
| SCHEMBL30230784 | 0.75 | CYP3A4 (0.41) | BRD4ALDH1A1SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL29710146 | 0.72 | ABL1 (0.39) | BRPF1BRD4NPC1ALDH1A1RAB9A | |
| SCHEMBL23165769 | 0.72 | ABL1 (0.39) | BRPF1BRD4NPC1ALDH1A1RAB9A | |
| SCHEMBL712310 | 0.69 | TSHR (0.48) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL31148268 | 0.68 | ALDH1A1 (0.42) | BRD4ALDH1A1MAPTPIK3CAPIK3CB | |
| SCHEMBL29349036 | 0.68 | ALDH1A1 (0.46) | BRPF1BRD4NPC1ALDH1A1RAB9A | |
| SCHEMBL25257971 | 0.68 | BRD4 (0.46) | BRPF1BRD4ANPEPDPP4NPC1 | |
| SCHEMBL25258821 | 0.68 | BRD4 (0.38) | BRPF1BRD4TP53MAPTPIK3CA | |
| SCHEMBL19390809 | 0.67 | AR (0.54) | ANPEPDPP4ALDH1A1MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |
| US-20230227427-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-07-20 | — | — | US | disclosed |
| EP-4157827-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227427-A1 | IL-17A MODULATORS | IL17A, IL2, IL15 | BRPF1 3370/4885BRD4 1372/4885ANPEP 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.