Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867645 | 0.82 | ABCG2 (0.56) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16867661 | 0.82 | ABCG2 (0.61) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1000085 | 0.79 | ABCG2 (0.67) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19086304 | 0.78 | ABCG2 (0.78) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19086305 | 0.78 | ABCG2 (0.78) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30384556 | 0.77 | PTPN1 (0.60) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25200700 | 0.77 | PTPN1 (0.60) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16865561 | 0.74 | NFKB1 (0.54) | ABCG2NFKB1NFKB2RELA | |
| SCHEMBL16865560 | 0.74 | ABCG2 (0.50) | ABCG2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL25217986 | 0.72 | ABCG2 (1.00) | ABCG2MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |