Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25200700 | 1.00 | PTPN1 (0.60) | PTPN1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL25254874 | 0.77 | ABCG2 (0.55) | KMT2AMEN1CYP3A4MAPTNFKB1 | |
| SCHEMBL22038894 | 0.75 | ATM (0.51) | KMT2AMEN1CYP3A4MAPTTDP1 | |
| SCHEMBL3184205 | 0.75 | AKT1 (0.56) | MAPTTDP1ESR1ESR2PKM | |
| SCHEMBL30513267 | 0.75 | AKT1 (0.56) | MAPTTDP1ESR1ESR2PKM | |
| SCHEMBL30383083 | 0.75 | PTPN1 (1.00) | PTPN1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL16867661 | 0.74 | ABCG2 (0.61) | KMT2AMEN1CYP3A4MAPTHPGD | |
| SCHEMBL847088 | 0.74 | ALOX5 (0.52) | CYP3A4MAPTHPGDAPPBACE1 | |
| SCHEMBL847089 | 0.74 | ALOX5 (0.52) | CYP3A4MAPTHPGDAPPBACE1 | |
| SCHEMBL25241260 | 0.74 | MAPT (0.66) | PTPN1KMT2AMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |