Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5467040 | 0.92 | TRPV1 (0.44) | MBOAT4TRPV1GRM5KCNQ3KCNQ2 | |
| SCHEMBL27976093 | 0.86 | TRPV1 (0.44) | TRPV1PTGS2 | |
| Acetonitrile SCHEMBL27976111 | 0.81 | TRPV1 (0.41) | TRPV1PTGS2 | |
| Hydrochloric Acid SCHEMBL28391819 | 0.79 | MEN1 (0.37) | TRPV1 | |
| SCHEMBL2526697 | 0.79 | TRPV1 (0.47) | TRPV1CDK1PTGS2 | |
| SCHEMBL27885274 | 0.77 | TRPV1 (0.42) | TRPV1CDK1PTGS2MAT2A | |
| SCHEMBL6806025 | 0.77 | MBOAT4 (0.42) | MBOAT4TRPV1GRM5IRAK4CDK1 | |
| SCHEMBL2531612 | 0.77 | TRPV1 (0.49) | MBOAT4TRPV1 | |
| SCHEMBL2531620 | 0.75 | TRPV1 (0.48) | MBOAT4TRPV1 | |
| SCHEMBL2525510 | 0.74 | MBOAT4 (0.51) | MBOAT4TRPV1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940821-B1 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |
| EP-2388258-A1 | Novel vanilloid receptor ligands and their use for producing medicaments | Grünenthal GmbH (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-8038010-B1 | Single piece edge protector for curved objects | ILLINOIS TOOL WORKS INC. (US) | 2011-10-18 | — | — | US | disclosed |
| EP-1940821-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045462-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2007-04-26 | — | — | WO | disclosed |