Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.49 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5468763 | 0.93 | TRPV1 (0.51) | TRPV1MBOAT4MKNK1MKNK2 | |
| SCHEMBL27976092 | 0.85 | TRPV1 (0.44) | TRPV1MBOAT4CDK2KDR | |
| SCHEMBL2531620 | 0.84 | TRPV1 (0.48) | TRPV1MBOAT4MKNK1MKNK2CDK2 | |
| SCHEMBL2531610 | 0.80 | TRPV1 (0.49) | TRPV1MBOAT4 | |
| Acetonitrile SCHEMBL27975755 | 0.80 | TRPV1 (0.41) | TRPV1MBOAT4CDK2KDR | |
| SCHEMBL2529157 | 0.79 | TRPV1 (0.42) | TRPV1MBOAT4 | |
| Acetic Acid SCHEMBL5472294 | 0.78 | TRPV1 (0.50) | TRPV1MKNK1MKNK2 | |
| SCHEMBL2525513 | 0.77 | MBOAT4 (0.43) | TRPV1MBOAT4 | |
| Acetic Acid SCHEMBL5468766 | 0.75 | TRPV1 (0.51) | TRPV1MBOAT4 | |
| SCHEMBL2526697 | 0.74 | TRPV1 (0.47) | TRPV1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940821-B1 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |
| EP-2388258-A1 | Novel vanilloid receptor ligands and their use for producing medicaments | Grünenthal GmbH (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-8038010-B1 | Single piece edge protector for curved objects | ILLINOIS TOOL WORKS INC. (US) | 2011-10-18 | — | — | US | disclosed |
| EP-1940821-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045462-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2007-04-26 | — | — | WO | disclosed |