Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5460638 | 0.93 | TRPV1 (0.49) | TRPV1PTGS2PTGS1CCNB2CDK1 | |
| SCHEMBL27976092 | 0.80 | TRPV1 (0.44) | TRPV1PTGS1CDK1CDK2 | |
| SCHEMBL12167678 | 0.80 | CNR2 (0.46) | TRPV1PTGS2PTGS1CNR2 | |
| SCHEMBL25511041 | 0.79 | TRPV1 (0.45) | TRPV1PTGS2PTGS1CCNB2CDK1 | |
| SCHEMBL2525513 | 0.79 | MBOAT4 (0.43) | TRPV1PTGS2CDK1 | |
| SCHEMBL2526695 | 0.77 | TRPV1 (0.47) | TRPV1PTGS2PTGS1CCNB2CDK1 | |
| SCHEMBL2525496 | 0.77 | SLC6A4 (0.44) | TRPV1PTGS2PTGS1CCNA2CDK2 | |
| SCHEMBL2530058 | 0.76 | PTGS2 (0.44) | TRPV1PTGS2PTGS1CCNA2CDK2 | |
| SCHEMBL2529965 | 0.76 | TRPV1 (0.47) | TRPV1PTGS2PTGS1CCNB2CDK1 | |
| SCHEMBL25511040 | 0.76 | TRPV1 (0.45) | TRPV1PTGS2PTGS1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940821-B1 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |
| EP-2388258-A1 | Novel vanilloid receptor ligands and their use for producing medicaments | Grünenthal GmbH (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-8038010-B1 | Single piece edge protector for curved objects | ILLINOIS TOOL WORKS INC. (US) | 2011-10-18 | — | — | US | disclosed |
| EP-1940821-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045462-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THEIR USE FOR PRODUCING MEDICAMENTS | Grünenthal GmbH (DE) | 2007-04-26 | — | — | WO | disclosed |