Phosphohydantocidin

Phosphohydantocidin

SCHEMBL2525635

O=C1NC(=O)[C@@]2(N1)O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADSS2 P30520 2/20 1.00
PYGB P11216 4/20 0.57
PYGL P06737 3/20 0.57
PYGM P11217 2/20 0.57
FBP1 P09467 1/20 0.45
UMPS P11172 2/20 0.35
DNPH1 O43598 1/20 0.35
HPRT1 P00492 1/20 0.35
IGF2R P11717 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydantocidin SCHEMBL10339110 0.77 PYGB (0.90) ADSS2PYGBPYGLPYGM
SCHEMBL9736981 0.69 ADSS2 (0.52) ADSS2FBP1DNPH1IGF2R
Fructose 1,6-Diphosphate SCHEMBL168245 0.69 ADSS2 (0.52) ADSS2FBP1UMPSIGF2R
SCHEMBL8056 0.69 ADSS2 (0.52) ADSS2FBP1DNPH1IGF2R
Fructose 1,6-Diphosphate SCHEMBL19133126 0.69 ADSS2 (0.52) ADSS2FBP1UMPSIGF2R
SCHEMBL1493046 0.69 ADSS2 (0.52) ADSS2FBP1DNPH1IGF2R
SCHEMBL2591882 0.69 ADSS2 (0.52) ADSS2FBP1DNPH1IGF2R
Fructose 1,6-Diphosphate SCHEMBL14905889 0.69 ADSS2 (0.52) ADSS2FBP1UMPSIGF2R
Fructose 1,6-Diphosphate SCHEMBL166666 0.69 ADSS2 (0.52) ADSS2FBP1UMPSIGF2R
Fosfructose SCHEMBL20731194 0.69 ADSS2 (0.52) ADSS2FBP1UMPSIGF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023177312-A2 INHIBITOR OF CELLULAR PURINE NUCLEOTIDE SALVAGE PATHWAY ENZYME FOR USE IN THE TREATMENT AND/OR PREVENTION OF HELICOBACTER PYLORI INFECTION AND/OR DISEASE ASSOCIATED WITH SUCH INFECTION AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME UNIWERSYTET WARSZAWSKI (PL) 2023-09-21 WO claimed
WO-2023177312-A2 INHIBITOR OF CELLULAR PURINE NUCLEOTIDE SALVAGE PATHWAY ENZYME FOR USE IN THE TREATMENT AND/OR PREVENTION OF HELICOBACTER PYLORI INFECTION AND/OR DISEASE ASSOCIATED WITH SUCH INFECTION AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME UNIWERSYTET WARSZAWSKI (PL) 2023-09-21 WO disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 EP disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
US-8036831-B2 Ligand searching device, ligand searching method, program, and recording medium IN-SILICO SCIENCES, INC. (JP) 2011-10-11 US disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed
US-20070166760-A1 Ligand searching device, ligand searching method, program, and recording medium IN-SILICO SCIENCES, INC. 2007-07-19 US disclosed
EP-1724697-A1 LIGAND SEARCHING DEVICE, LIGAND SEARCHING METHOD, PROGRAM, AND RECORDING MEDIUM In-Silico Sciences, Inc. (JP) 2006-11-22 EP disclosed