Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301636 | 0.92 | SOS1 (0.46) | SOS1TNFCXCL8NOD2NOD1 | |
| SCHEMBL8671917 | 0.77 | SOS1 (0.52) | SOS1TNFCXCL8NOD2NOD1 | |
| SCHEMBL25262400 | 0.75 | ALDH1A1 (0.53) | SOS1TNFCXCL8NOD2NOD1 | |
| SCHEMBL30581430 | 0.75 | ALDH1A1 (0.53) | SOS1TNFCXCL8NOD2NOD1 | |
| SCHEMBL30581414 | 0.75 | POLB (0.49) | SOS1TNFCXCL8NOD2NOD1 | |
| SCHEMBL25299930 | 0.72 | ALDH1A1 (0.46) | SOS1TNFCXCL8NOD2NOD1 | |
| SCHEMBL30586461 | 0.72 | ALDH1A1 (0.46) | SOS1TNFCXCL8NOD2NOD1 | |
| SCHEMBL5479265 | 0.71 | SLC2A1 (0.43) | KMT2ATRAP1ALDH1A1CDC25ACDC25B | |
| SCHEMBL14247342 | 0.71 | BRD4 (0.47) | SOS1TNFCXCL8NOD2NOD1 | |
| Nitrous Acid SCHEMBL25426326 | 0.70 | POLB (0.44) | SOS1TNFCXCL8NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401531-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |