Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 14/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581430 | 1.00 | ALDH1A1 (0.53) | ALDH1A1POLBHTTCSF1RSOS1 | |
| SCHEMBL16763065 | 0.76 | CSF1R (0.76) | CSF1RNTRK1NTRK2 | |
| SCHEMBL30581414 | 0.76 | POLB (0.49) | ALDH1A1POLBHTTSOS1NPSR1 | |
| SCHEMBL25301636 | 0.75 | SOS1 (0.46) | ALDH1A1POLBHTTSOS1NPSR1 | |
| SCHEMBL25258182 | 0.75 | SOS1 (0.44) | ALDH1A1POLBHTTSOS1MEN1 | |
| SCHEMBL25255010 | 0.75 | ALDH1A1 (0.41) | ALDH1A1POLBHTTCSF1RNTRK1 | |
| SCHEMBL30581404 | 0.75 | ALDH1A1 (0.41) | ALDH1A1POLBHTTCSF1RNTRK1 | |
| SCHEMBL25299930 | 0.73 | ALDH1A1 (0.46) | ALDH1A1POLBHTTSOS1KMT2A | |
| SCHEMBL30586461 | 0.73 | ALDH1A1 (0.46) | ALDH1A1POLBHTTSOS1KMT2A | |
| SCHEMBL25258958 | 0.71 | GAA (0.44) | ALDH1A1NPSR1MEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |