⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11854717 | 0.98 | L3MBTL1 (0.48) | — | |
| SCHEMBL14662105 | 0.85 | PLA2G4A (0.41) | — | |
| SCHEMBL2899167 | 0.82 | HDAC1 (0.41) | — | |
| SCHEMBL3708531 | 0.79 | — | — | |
| SCHEMBL1788277 | 0.79 | — | — | |
| SCHEMBL1974224 | 0.79 | — | — | |
| SCHEMBL6786585 | 0.78 | ALDH1A1 (0.63) | — | |
| SCHEMBL12241846 | 0.77 | — | — | |
| SCHEMBL2701014 | 0.77 | HDAC6 (0.59) | — | |
| SCHEMBL1810306 | 0.76 | PLA2G4A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 871 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4585589-A2 | STEM CELL CULTURES | The Scripps Research Institute (US) | 2025-07-16 | — | — | EP | claimed |
| CN-108546225-B | Process for producing nitrile and corresponding amine | 中国石化扬子石油化工有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-106632057-B | A kind of ionic liquid and the method for being synthesized by Thiazovivin | 中国农业科学院兰州畜牧与兽药研究所 | 2019-06-25 | — | — | CN | claimed |
| CN-106632057-A | Ionic liquid and method for synthesizing Thiazovivin by same | 中国农业科学院兰州畜牧与兽药研究所 | 2017-05-10 | — | — | CN | claimed |
| EP-2231654-B1 | NEW 2-SUBSTITUTED TIAZOL-4-CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURE AND USE AS MEDICINE | BAYER IP GMBH (DE) | 2013-07-03 | — | — | EP | claimed |
| CN-103145711-A | Azaadamantane ester and carbamate derivatives and methods of use thereof | ABBOTT LAB | 2013-06-12 | — | — | CN | claimed |
| EP-2231652-B1 | NOVEL 2-HETARYL THIAZOLE-4-CARBOXAMIDE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | Bayer Pharma AG (DE) | 2012-05-30 | — | — | EP | claimed |
| US-8148411-B2 | 2-hetarylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-04-03 | — | — | US | claimed |
| EP-2129672-B1 | AZAADAMANTANE ESTER AND CARBAMATE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LAB (US) | 2011-05-18 | — | — | EP | claimed |
| EP-2240457-B1 | NOVEL 2-ARYL-THIAZOLE-4-CARBOXAMIDE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | BAYER SCHERING PHARMA AG (DE) | 2011-05-11 | — | — | EP | claimed |
| CN-101641355-A | Azaadamantane ester and carbamate derivatives and methods of use thereof | ABBOTT LAB US | 2010-02-03 | — | — | CN | claimed |
| US-20090203715-A1 | NOVEL 2-HETARYLTHIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | BAYER SCHERING PHARMA AG (DE) | 2009-08-13 | — | — | US | claimed |
| US-20090163486-A1 | Novel 2-arylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-06-25 | — | — | US | claimed |
| WO-2009074234-A1 | NOVEL 2-SUBSTITUTED THIAZOLE-4-CARBOXAMIDE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | claimed |
| WO-2009074247-A1 | NOVEL 2-ARYL-THIAZOLE-4-CARBOXAMIDE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | claimed |
| WO-2009074246-A1 | NOVEL 2-HETARYL THIAZOLE-4-CARBOXAMIDE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | claimed |
| EP-2070925-A1 | New 2-substituted tiazol-4-carboxylic acid derivatives, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | claimed |
| EP-2070916-A1 | 2-Arylthiazol-4-carboxylic acid derivatives, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | claimed |
| EP-2070924-A1 | New 2 hetarylthiazol-4-carboxylic acid derivatives, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | claimed |
| US-20090149517-A1 | NOVEL 2-SUBSTITUTED TIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-06-11 | — | — | US | claimed |